Friday, 9 September 2005

This presentation is part of: AMS in Low Dose Biosciences Posters

Measurement of 41Ca in biomedical samples with a 600 kV AMS system

Martin Stocker1, Max Döbeli2, Michal Grajcar1, Martin Suter2, Hans-Arno Synal2, and Lukas Wacker2. (1) Institute of Particle Physics, ETH Zurich, ETH Hönggerberg, HPK H29, Schafmattstrasse 20, Zurich, 8093, Switzerland, (2) Paul Scherrer Institute c/o ETH Hönggerberg, ETH Zürich, Zürich, Switzerland

Age-related osteoporosis is a major and increasing public health problem which has a considerable impact in terms of enhanced morbidity, mortality and reduced quality of life. In addition it places an increasing burden on health care systems. In the context of osteoporosis research 41Ca is used as a tracer to examine the influence of dietary factors on bone metabolism.

We present first results of 41Ca measurements of CaF2 samples using a compact 600 keV AMS system. By using CaF2 material, sample preparation and handling is simple. With CaF3- extracted from the ion source, a transmission of 6-14% was obtained and a background level of 3 10-12 was found.

A series of biomedical samples from the European OSTEODIET Project have been measured with this system and compared to the values obtained with a 6 MeV AMS facility using the CaH3 method. The results are in good agreement and demonstrate that the performance of the compact AMS facility is sufficient for many biomedical applications.


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See more of The 10th International Conference on Accelerator Mass Spectrometry (September 5-10, 2005)